Orudis hög
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Orudis
WARNINGS
CARDIOVASCULAR EFFECTS
Cardiovascular Thrombotic Events
Clinical trials of several COX-2 selective and nonselective NSAIDs of up to three years duration have shown an increased risk of serious cardiovascular (CV) thrombotic events, myocardial infarction, and stroke, which can be fatal. All NSAIDs, both COX-2 selective and nonselective, may have a similar risk. Patients with known CV disease or fara factors for CV disease may be at greater risk. To minimize the potential fara for an adverse CV event in patients treated with an NSAID, the lowest effective dose should be used for the shortest duration possible. Physicians and patients should remain alert for the development of such events, even in the absence of previous CV symptoms. Patients should be informed about the signs and/or symptoms of serious CV events and the steps to take if they occur.
There fryst vatten no consistent evidence that concurrent use of smärtstillande medicin mitigates the increased fara of serious CV thrombotic events associated with NSAID use. The concurrent use of smärtstillande medicin and an NSAID does increase the risk of serious GI events (see WARNINGS - Gastrointestinal Effects: Risk of Ulceration, Bleeding,
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Orudis Ketoprofen uses, dose and side effects
% gel
ketoprofen
What Orudis is and what it is used for
Orudis contains the active substance ketoprofen, which belongs to a group of medicines called non-steroidal anti-inflammatory / anti-rheumatic drugs ( NSAIDs ). It is a topical drug used on the skin to relieve pain and reduce inflammation locally where the damage is.
Orudis is used for mild to moderate pain in connection with muscle and/or joint injuries, such as sports injuries.
What you need to know before using Orudis
Do not use Orudis
- If you are allergic to ketoprofen or any of the other ingredients of Orudis (see section 6).
- If you have ever had a hypersensitivity reaction (eg symptoms of asthma , hay fever, hives ) while taking fenofibrate, acetylsalicylic acid or other NSAIDs .
- If you have eczema (scaly, itchy skin rash), acne , infection or open sores in the treatment area.
- If you are in any of the last three months of a pregnancy.
- If you have ever had an abnormal skin reaction to sunlight.
- If you have known allergies to ketoprofen , thiapro
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Consumer medicine information
1 Name of Medicine
Ketoprofen.
2 Qualitative and Quantitative Composition
Each Orudis SR capsule contains ketoprofen mg.
For the full list of excipients, see Section List of Excipients.3 Pharmaceutical Form
Orudis SR Capsules: modified release, hard gelatin capsule. Clear pink base and white opaque cap. Base and cap printed 'ORUDIS SR ' and contains off-white to cream spherical pellets.
4 Clinical Particulars
Therapeutic Indications
Rheumatoid arthritis, osteoarthritis.
Dose and Method of Administration
After assessing the risk/ benefit ratio in each individual patient, the lowest effective dose for the shortest possible duration should be used (see Section Special Warnings and Precautions for Use). Patients on long-term treatment should be reviewed regularly with regards to efficacy, risk factors and ongoing need for treatment.
Orudis SR (sustained release) capsules.
mg once daily depending on the patient's weight and on the severity of symptoms. Orudis SR should be taken with food.Use in the elderly.
It is generally advisable in the elderly to begin ketoprofen therapy at the lower end of the dosage range and to maintain such p